Prof Tanneke den Blauween, our supervisor from the University of Amsterdam co-organises the EMBO Workshop on bacterial cell division in Lund, Sweden this June, while supervisor Waldemar Vollmer from the Newcastle University will be one of the speakers.
The workshop aims at bringing together both established experts and early career researchers to discuss recent major advances in our understanding of the molecular mechanisms of cell division, as well as novel aspects of division and its regulation in non-model bacteria, antibiotic target selection and drug development.
We are now also on Instagram! Joined by our roster of ESR that already cover the website and Twitter, you can now follow us to get news about the Consortium, some interesting trivia about antibiotic research and some fun facts to start the week in a great mood.
See you at @train2target ! #mariecurie #train2target #TogetherForScience
Beginning of October marked the kick-off of another working year in our Consortium, with our 2nd Annual Meeting in Naples, Italy.
This was the first time all the ESRs had the chance to presente their results to the entire Consortium after a full year of work.
The meeting was marked by good weather, exciting scientific discussions and an amazing and very warming city, and we are already excited to announce we started planning next year's Annual Meeting.
Stay tuned for more updates.
The European Researchers’ Night is a Marie Sklodowska Curie (MSCA) action, under the EU Framework Programme for Research and Innovation Horizon 2020; it consists of a pan-European event taking place on the last Friday night of September.
The 2018 European Researcher’s Night took place on 27th and 28th of September. During these days, there were many science dissemination activities in different cities of Europe.
In Italy the event (MEETmeTONIGHT) was conducted in Milan and Naples.
On Monday 5th February, Train to target (T2T) Early Stage Researchers (ESR) attended the webinar “Envelope biogenesis and signaling systems” by Prof. Jean-François Collet.
The presentation aimed to disclose the key components of the complex macromolecular structure of the Gram-negative bacteria cell envelope.
Gram-negative bacteria possess a complex envelope. In addition to the inner cytoplasmic membrane, the bacteria have an extra membrane layer that faces the external environment and provides a formidable barrier against antibiotics.
Prof. Collet presented an overview of the biogenesis of this cell envelope and the diverse structures immersed in it. He detailed the function, synthesis and transportation machineries of: peptidoglycan, lipopolysaccharides, phospholipids and membrane proteins (lipoproteins, beta-barrel proteins and soluble proteins). Also, he highlighted the remaining open questions of the scientific community on those subjects. Giving answer to some of those questions is the principal objective of the T2T program and main goal of the ESR´s PhD projects.
Without the slightest doubt, this lecture was a very interesting starting point of the remote training sessions. We are looking forward to the next one.
Acknowledgements to Pilar Garcia del Vello Moreno (ESR10) for writing this webinar report.
Szewczyk, J., and Collet J.F. (2016) The Journey of Lipoproteins Through the Cell: One Birthplace, Multiple Destinations. Advances in Microbial Physiology 69, 1-50.
Our first Annual Meeting in Albufeira in September 2017 has been a great success.
The first Annual Meeting is currently under planning and will take place in Portugal from 28th - 29th of September 2017.
A new report from the European Centre for Disease Prevention and Control (ECDC) reveals that resistance has continued to increase across Europe in spite of attempts to raise global awareness of the danger to the fundamentally important antibiotic class of drugs. Without them, some infectious diseases could become untreatable and some forms of major surgery would again become perilous.
The report, released on the occasion of the 9th European Antibiotic Awareness Day, is based on the latest EU-wide data on antibiotic resistance and antibiotic consumption. In 2015, antibiotic resistance continued to increase for most bacteria and antibiotics under surveillance. In particular, the EU average percentage of carbapenem resistance in Klebsiella pneumoniae increased from 6.2% in 2012 to 8.1% in 2015, and combined resistance to carbapenems and polymyxins (e.g. colistin) was sometimes reported. These two groups of antibiotics are considered last-line antibiotics as they usually are the last treatment options for patients infected with bacteria resistant to other available antibiotics. While antibiotic consumption in hospitals significantly increased in several EU Member States, antibiotic consumption in the community decreased in six EU Member States.
Since 1983, the APUA Newsletter has been a continuous source of non-commercial information disseminated without charge to healthcare practitioners, researchers, and policy-makers worldwide. The Newsletter carries up-to-date scientific and clinical information on prudent antibiotic use, antibiotic access and effectiveness, and management of antibiotic resistance. The publication is distributed to over 7,000 affiliated individuals in more than 100 countries.
An influential report sponsored by the British Government and assembled by Lord Jim O’Neill suggests that the scourge of antimicrobial resistance can be effectively tackled. By launching targeted public awareness campaigns about the proper use of antibiotics, reducing the intake of antibiotics by livestock and humans, and simultaneously increasing the number of antibiotics available on the shelves, the O’Neill report concludes that combating antimicrobial resistance is not just possible, but also affordable. While the economic cost of antimicrobial resistance is predicted to be $100 trillion a year by 2050, the cost of action against rising resistance is estimated to be a much more modest $40 billion dollars a decade. Furthermore, the report provides accompanying recommendations to reduce resistance that include prohibiting the use of antibiotics that are vital to humans in livestock, carefully surveying the administration of drugs in developing countries, improving sanitation and hygiene to reduce risk of infection and disease, using rapid and specific diagnostic techniques to distinguish between bacterial infections and other infections, administrating vaccines and other alternatives to antibiotics, and forming an international coalition for action and a global innovation fund.