ESR 6: Laureen Mertens
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Assembly and dynamics of the LPS transport Lpt machinery and coordination with peptidoglycan (PG) synthetic machineries
Laureen will determine whether Lpt is a permanent or a dynamic complex by analysing the periplasmic interactome of the Lpt complex, checking dependency on substrate for Lpt assembly. Furthermore, Laureen is tasked with assessing whether the Lpt complex and the PG synthetic machineries are able to monitor each others functions and with the development of an in vivo screening assay that reports on the block of LPS assembly pathway. |
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Host:
University of Amsterdam, Swammerdam Institute for Life Sciences, The Netherlands Supervisory Team: Prof. Tanneke den Blaauwen (UvA) Prof. Alessandra Polissi (UNIMI) Prof. Waldemar Vollmer (UNEW) Scientific Background: Laureen Mertens has a bachelor's degree in Life, Science & Technology from the Delft University of Technology and Leiden University, NL and a Master's degree in Molecular Microbiology, Microbial Ecology and Immunobiology from the University of Vienna, Austria. In het Master's thesis, she has developed a CRISPR system to allow genetic modification of Sulfolobus solfataricus. She has a background in biophysics, biotechnology and molecular microbiology, with some management and educational experience.. |
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