ESR 13: Arancha Lopez Perez
Identification and characterization of innovative Penicillin-Binding Protein inhibitors against MDR-Gram negative bacteria.
Arancha will perform research in antibacterial drug discovery targeting Gram-negative pathogens, aiming to identify novel chemical classes to target key Peptidoglycan (PG) proteins of Gram-negative bacteria and to develop suitable biochemical target assays for hit evaluation. Furthermore, she will conduct testing of potential hit/ leads in animal models of infection and evaluate further bacterial targets and assays for antibacterial drug discovery.
AiCuris GmbH, Germany
Dr. Cuong Vuong (AiCuris)
Prof. Waldemar Vollmer (UNEW)
Prof. Jean-Pierre Simorre (CNRS)
Arancha López-Pérez holds a Bachelor of Biology from the Faculty of Science, Universidad Autonomous of Madrid, Spain (2012-2016). Further, she completed her Master in Microbiology at the same University ( 2016-2017).
During her Bachelor and Master, she worked with Pr. Wilfried JJ Meijer in CBMSO (Madrid). Arancha investigated for her Bachelor Thesis the "Functional and structural characterization of two genes from pLS20 plasmid that increase the fitness of Bacillus subtilis 168". She continued with her work on the same topic and completed her Master Thesis recently. She identified and characterized the function of these genes and its regulation.
Additionally, Arancha had the opportunity to participate in the Erasmus Placement Internship and broaden her scientific expertise on Phages and Staphylococci spp in the Pr. Jose Penadés laboratory at the Microbiology Department, Glasgow University.
Now, she has joined Dr. Cuong Vuong team in Aicuris (Wuppertal, Germany) for her PhD and she will work as well as with Pr.Waldemar in Newcastle University.