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      • ESR 5: Jessica El-Rayes
      • ESR 6: Laureen Mertens
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ESR 14: Matthias Winkle

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Coordination of peptidoglycan synthesis within outer membrane constriction and LPS synthesis

Matthias will perform research in bacterial cell envelope biogenesis using molecular biology and biochemical techniques. He will explore the connections between peptidoglycan synthesis and different trans-envelope machines. His main focus will be the link between peptidoglcyan synthesis and the Lpt complex in Gram-negative bacteria. Another task of Matthias will be to search for novel inhibitors of the peptidoglycan synthesis.

Host:
University of Newcastle Upon Tyne, Institute for Cell and Molecular Biosciences, United Kingdom

Supervisory Team:
Prof. Waldemar Vollmer (UNEW)
Prof. Tanneke den Blaauwen (UvA)
Prof. Alessandra Polissi (UNIMI)

Scientific Background:
Matthias Winkle holds a bachelor degree in Food Science and Biotechnology from the University of Hohenheim, Stuttgart, Germany. During his bachelor’s program he decided to focus his further studies on biotechnology and wrote his bachelor thesis at the Institute of Biotechnology and Enzyme Science. He then spend four months at the Centre of Bacterial Cell Biology, Newcastle University, United Kingdom where he focused on the peptidoglycan synthesis machinery during cell elongation. The visit at Newcastle leads to his fascination in cell and molecular bioscience. In June 2017 he joined the Train2Target multidisciplinary European Training Network as a PhD student at the University of Newcastle.
Science Slam: Peptidoglycan created by Matthias and Federico
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Contact:
m.winkle2@ncl.ac.uk

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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No 721484.

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